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(1985), Journal of Biological Chemistry, 260. Larger defects may require advancement flaps (see Rare Anal Neoplasms). J. Targeted deletion of BMK1ERK5 in adult mice perturbs vascular integrity and leads to endothelial failure.1254, 1984. The diagnosis of familial MTC in index cases is often made postopera- tively when histopathological examination may show multifocal bilateral MTC accompanied by diffuse C-cell hyperplasia. Based on this bilaterality, the paperвs discussion ends with the proposal that a more appropriate term for this entity is diffuse subacute neuroretinitis.

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